Navigating Patient Selection

Situation

A client developing a new therapy sought to prioritize the indication for clinical development with the highest likelihood of technical and commercial success.

Task

Rank indication options by relative scientific rationale, competitive density, most-likely market evolution and addressable patient populations.

Action

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Leveraged our scientific expertise to contextualize lessons learned from technically-analogous approaches, highlighting challenges, inflection points in the field and data gaps.
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Curated historical proof-of-concept data.
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Concisely conveyed competitive density and frontrunners in each indication of interest, along with the most likely market evolution.
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Tapped into our primary intel network to pinpoint key areas of unmet need, and addressable patient populations.
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Defined entry opportunities and challenges for top indications and framed these in terms of the client’s in-house assets and capabilities.
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Developed a comprehensive plan for continuous CI monitoring, including fast-turnaround email alerts that frame new developments in the context of our current narrative and shared assumptions.

Results

Based on our engagement, the client was able to prioritize two specifically-defined patient populations where they have the best chance of addressing unmet need and gaining market adoption with their technology. The client used our insights to communicate a defensible rationale and win confidence with investors and shareholders.
Identified the unmet need
Established the rationale
Won confidence with investors

Selected the Optimal

Patient Population

Please note: images are for illustrative purposes only.
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